Oxford Nanopore reports stronger-than-expected first half, shares slide

Oxford Nanopore Technologies shares were in the red on Tuesday morning, even after it reported a stronger-than-expected first half, with revenue growth across all regions and customer segments and a narrowed loss as it reaffirmed its full-year guidance.

  • Oxford Nanopore Technologies
  • 02 September 2025 10:03:24
Oxford Nanopore Technologies

Source: Sharecast

The FTSE 250 sequencing company posted revenue of £105.6m for the six months ended 30 June, up 25.6% year on year on a reported basis and 28% at constant currency.

Growth was broad-based, led by Asia-Pacific and EMEAI, which rose 38.3% and 32.7% respectively, while the Americas grew 16.9% despite what the company described as “ongoing uncertainty in the US research environment”.

Clinical markets grew 52.9%, followed by Applied Industrial, BioPharma and Research.

Adjusted EBITDA losses narrowed to £48.3m from £61.7m a year earlier, reflecting improved gross profits and cost control.

Its gross margin slipped by 60 basis points to 58.2% after a one-off £3.3m non-cash inventory charge and currency headwinds.

The net loss for the period reduced to £71.8m from £74.7m in the prior year.

“We delivered a strong first half performance, with broad-based growth across all geographies and customer segments,” said chief executive Gordon Sanghera.

“Revenue grew ahead of expectations, driven by increasing demand in both Research and Applied markets and further adoption of our high-output PromethION platform by customers across a wide range of applications.

“We also made clear progress on our path to profitability, with improved EBITDA performance reflecting expanding gross profit and disciplined cost control.”

The company highlighted operational progress including a new partnership with Cepheid, a subsidiary of Danaher, to develop automated infectious disease sequencing solutions, and advances in oncology and rare disease applications, industrial synthetic biology, and biopharma quality control.

Oxford Nanopore said it had refined its commercial strategy to target high-priority Applied and Research markets worth an estimated $13bn to $14bn.

The firm said ended the half with £337.3m in cash and investments, down from £403.8m at year-end, but said cash flow was improving as more customers opted for capital purchases rather than leasing.

Sanghera confirmed the company remained on track to meet full-year 2025 targets and medium-term objectives.

Those included 20% to 23% revenue growth this year, adjusted EBITDA breakeven by 2027, and positive cash flow in 2028, supported by revenue growth of over 30% per year at constant currency.

At 0943 BST, shares in Oxford Nanopore Technologies were down 3.51% at 178.8p.

Reporting by Josh White for Sharecast.com.

Exchange: London Stock Exchange
Sell:
0.00
Buy:
0.00
Change: 296.13 ( 1.40 %)
Date:
Prices delayed by at least 15 minutes

Compare our accounts

If you're looking to grow your money over the longer term (5+ years), we have a range of investment choices to help.

Lloyds Bank is not responsible for the content and accuracy of the Markets News articles. We may not share the views of the author. Understand the risks, please remember the value of your investment can go down as well as up and you may not get back the full amount you invest. We don't provide advice so if you are in any doubt about buying and selling shares or making your own investment decisions we recommend you seek advice from a suitably qualified Financial Advisor. Past performance is not a guide to future performance.

Important legal information

Lloyds and Lloyds Bank are trading names of Halifax Share Dealing Limited. The Lloyds Bank Direct Investments Service is operated by Halifax Share Dealing Limited. Registered Office: Trinity Road, Halifax, West Yorkshire, HX1 2RG. Registered in England and Wales no. 3195646. Halifax Share Dealing Limited is authorised and regulated by the Financial Conduct Authority, 12 Endeavour Square, London, E20 1JN under registration number 183332. A Member of the London Stock Exchange and an HM Revenue & Customs Approved ISA Manager.

Logo Allfunds

The information contained within this website is provided by Allfunds Digital, S.L.U. acting through its business division Digital Look Ltd unless otherwise stated. The information is not intended to be advice or a recommendation to buy, sell or hold any of the shares, companies or investment vehicles mentioned, nor is it information meant to be a research recommendation. This is a solution powered by Allfunds Digital, S.L.U. acting through its business division Digital Look Ltd incorporating their prices, data news, charts, fundamentals and investor tools on this site. Terms and conditions apply. Prices and trades are provided by Allfunds Digital, S.L.U. acting through its business division Digital Look Ltd and are delayed by at least 15 minutes.

FE fundinfo Logo

Data provided by FE fundinfo. Care has been taken to ensure that the information is correct, but FE fundinfo neither warrants, represents nor guarantees the contents of information, nor does it accept any responsibility for errors, inaccuracies, omissions or any inconsistencies herein. Past performance does not predict future performance, it should not be the main or sole reason for making an investment decision. The value of investments and any income from them can fall as well as rise.

Refinitiv Logo

© 2025 Refinitiv, an LSEG business. All rights reserved.